Effects of modified Bushen Huoxue Prescription combined with active immunotherapy on immunomodulatory functions and pregnancy outcomes of patients with unexplained recurrent spontaneous abortion
نویسندگان
چکیده
To assess the effects of modified Bushen Huoxue Prescription combined with active immunotherapy on immunomodulatory functions and pregnancy outcomes URSA patients. Ninety-six eligible patients were randomly divided into control experimental groups (n=48). Active was performed for group, while group treated immunotherapy. Counts peripheral blood helper T lymphocytes 17 (Th17) regulatory (Treg), levels inflammatory factors interleukin-4 (IL-4), IL-10 IL-17, mRNA expression retinoic acid-related orphan receptor γt (RORγt) forkhead box P3 (FoxP3) compared. Compared before treatment, ratios Th17/CD4+ cells Th17/Treg, IL-17 level RORγt decreased, whereas ratio Treg/CD4+ cells, IL-4 FoxP3 increased in both after treatment (P<0.05). After lower than those IL-4, higher Modified worked well to improve abortion rate.
منابع مشابه
O-26: The Value of Hysteroscopy in Diagnosis of Chronic Endometritis in Patients with Unexplained Recurrent Spontaneous Abortion
Background: We performed this study in order to investigate the role of chronic endometritis (CE) in unexplained recurrent spontaneous abortion (RSA) and to determine the correlation between hysteroscopic and histologic findings of CE in patients with unexplained RSA. We also tried to find out the relation between CE and primary vs. secondary RSA. Materials and Methods: One hundred and forty-two ...
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ژورنال
عنوان ژورنال: Indian Journal of Experimental Biology
سال: 2023
ISSN: ['0019-5189']
DOI: https://doi.org/10.56042/ijeb.v61i07.2468